Gene

crls1

ID

ZDB-GENE-040426-2519

Name

cardiolipin synthase 1

Symbol

crls1 Nomenclature History

Previous Names

zgc:85909

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable cardiolipin synthase activity. Predicted to be involved in cardiolipin biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human CRLS1 (cardiolipin synthase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7139306 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With crls1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
combined oxidative phosphorylation deficiency 57	Alliance	Combined oxidative phosphorylation deficiency 57	620167

Associated With crls1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR000462	CDP-alcohol phosphatidyltransferase
Family	IPR050324	CDP-alcohol phosphatidyltransferase class-I
Homologous_superfamily	IPR043130	CDP-alcohol phosphatidyltransferase, transmembrane domain