Gene
ak4
- ID
- ZDB-GENE-040426-2505
- Name
- adenylate kinase 4
- Symbol
- ak4 Nomenclature History
- Previous Names
-
- ak3l1
- wu:fc37g02
- zgc:85790
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in AMP metabolic process and nucleoside triphosphate biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be active in mitochondrial matrix. Is expressed in axis; nervous system; neural tube; pronephric duct; and somite. Orthologous to several human genes including AK4 (adenylate kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85790 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR033690 | Adenylate kinase, conserved site |
| Domain | IPR007862 | Adenylate kinase, active site lid domain |
| Family | IPR000850 | Adenylate kinase/UMP-CMP kinase |
| Family | IPR006259 | Adenylate kinase subfamily |
| Family | IPR028585 | Adenylate kinase 4, mitochondrial |
| Family | IPR028586 | Adenylate kinase 3/4, mitochondrial |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036193 | Adenylate kinase, active site lid domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Adenylate kinase 3/4, mitochondrial | Adenylate kinase 4, mitochondrial | Adenylate kinase, active site lid domain | Adenylate kinase, active site lid domain superfamily | Adenylate kinase, conserved site | Adenylate kinase subfamily | Adenylate kinase/UMP-CMP kinase | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NUY0 | InterPro | 226 |
Interactions and Pathways
No data available
Plasmids
No data available