Gene
rad51d
- ID
- ZDB-GENE-040426-2490
- Name
- RAD51 paralog D
- Symbol
- rad51d Nomenclature History
- Previous Names
-
- zgc:77165 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process. Predicted to localize to Rad51B-Rad51C-Rad51D-XRCC2 complex; centrosome; and chromosome. Human ortholog(s) of this gene implicated in hereditary breast ovarian cancer syndrome. Orthologous to human RAD51D (RAD51 paralog D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77165 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Breast-ovarian cancer, familial, susceptibility to, 4} | 614291 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013632 | DNA recombination and repair protein Rad51-like, C-terminal |
| Domain | IPR020588 | DNA recombination and repair protein RecA-like, ATP-binding domain |
| Domain | IPR047323 | DNA repair protein RAD51 homolog 4, C-terminal |
| Domain | IPR048943 | RAD51D, N-terminal domain |
| Family | IPR016467 | DNA recombination and repair protein, RecA-like |
| Family | IPR051988 | Homologous Recombination Repair RAD51 Paralog |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | DNA recombination and repair protein Rad51-like, C-terminal | DNA recombination and repair protein, RecA-like | DNA recombination and repair protein RecA-like, ATP-binding domain | DNA repair protein RAD51 homolog 4, C-terminal | Homologous Recombination Repair RAD51 Paralog | P-loop containing nucleoside triphosphate hydrolase | RAD51D, N-terminal domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PJU0
|
167 | |||||||
|
UniProtKB:F1R474
|
327 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rad51d-201
(1)
|
Ensembl | 1,431 nt |
Interactions and Pathways
No data available
Plasmids
No data available