Gene
rad51d
- ID
- ZDB-GENE-040426-2490
- Name
- RAD51 paralog D
- Symbol
- rad51d Nomenclature History
- Previous Names
-
- zgc:77165 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable ATP-dependent activity, acting on DNA and single-stranded DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA repair. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Predicted to be active in microtubule organizing center and replication fork. Human ortholog(s) of this gene implicated in hereditary breast ovarian cancer syndrome. Orthologous to human RAD51D (RAD51 paralog D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77165 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Breast-ovarian cancer, familial, susceptibility to, 4} | 614291 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013632 | DNA recombination and repair protein Rad51-like, C-terminal |
| Domain | IPR020588 | DNA recombination and repair protein RecA-like, ATP-binding domain |
| Domain | IPR047323 | DNA repair protein RAD51 homolog 4, C-terminal |
| Domain | IPR048943 | RAD51D, N-terminal domain |
| Family | IPR016467 | DNA recombination and repair protein, RecA-like |
| Family | IPR051988 | Homologous Recombination Repair RAD51 Paralog |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | DNA recombination and repair protein Rad51-like, C-terminal | DNA recombination and repair protein, RecA-like | DNA recombination and repair protein RecA-like, ATP-binding domain | DNA repair protein RAD51 homolog 4, C-terminal | Homologous Recombination Repair RAD51 Paralog | P-loop containing nucleoside triphosphate hydrolase | RAD51D, N-terminal domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PJU0
|
167 | |||||||
|
UniProtKB:F1R474
|
327 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rad51d-201
(1)
|
Ensembl | 1,431 nt |
Interactions and Pathways
No data available
Plasmids
No data available