ZFIN is now using GRCz12tu for Genomic Data
Gene
nsun5
- ID
- ZDB-GENE-040426-2476
- Name
- NOP2/Sun RNA methyltransferase 5
- Symbol
- nsun5 Nomenclature History
- Previous Names
-
- wu:fc49f12
- zgc:66176
- zgc:77183 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA binding activity and RNA methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to act upstream of or within RNA methylation. Predicted to be active in nucleolus. Orthologous to several human genes including NSUN5 (NOP2/Sun RNA methyltransferase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77183 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001678 | SAM-dependent methyltransferase RsmB-F/NOP2-type domain |
| Domain | IPR048889 | NSUN5/RCM1, N-terminal domain |
| Domain | IPR049560 | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core |
| Domain | IPR049561 | NOL1/NOP2/NSUN 5/7, ferredoxin-like domain |
| Family | IPR023267 | RNA (C5-cytosine) methyltransferase |
| Homologous_superfamily | IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | NOL1/NOP2/NSUN 5/7, ferredoxin-like domain | NSUN5/RCM1, N-terminal domain | RNA (C5-cytosine) methyltransferase | S-adenosyl-L-methionine-dependent methyltransferase superfamily | SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core | SAM-dependent methyltransferase RsmB-F/NOP2-type domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NZ28 | InterPro | 435 | ||||||
| UniProtKB:A0A8M3BD27 | InterPro | 483 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers