Gene
cbwd
- ID
- ZDB-GENE-040426-2388
- Name
- COBW domain containing
- Symbol
- cbwd Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Enables GTPase activity and zinc chaperone activity. Involved in intracellular zinc ion homeostasis. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to several human genes including ZNG1C (Zn regulated GTPase metalloprotein activator 1C); ZNG1E (Zn regulated GTPase metalloprotein activator 1E); and ZNG1F (Zn regulated GTPase metalloprotein activator 1F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6897687 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Weiss et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003495 | CobW/HypB/UreG, nucleotide-binding domain |
| Domain | IPR011629 | Zinc chaperone CobW-like, C-terminal |
| Family | IPR051316 | Zinc-regulated GTPase metalloprotein activator |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036627 | CobW-like, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CobW/HypB/UreG, nucleotide-binding domain | CobW-like, C-terminal domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Zinc chaperone CobW-like, C-terminal | Zinc-regulated GTPase metalloprotein activator |
|---|---|---|---|---|---|---|
|
UniProtKB:B0R0B1
|
366 |
Interactions and Pathways
No data available
Plasmids
No data available