Gene
vdac3
- ID
- ZDB-GENE-040426-2380
- Name
- voltage-dependent anion channel 3
- Symbol
- vdac3 Nomenclature History
- Previous Names
-
- wu:fb01e12
- zgc:77898 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable voltage-gated monoatomic anion channel activity. Acts upstream of or within fin regeneration. Predicted to be located in membrane and mitochondrion. Predicted to be part of pore complex. Predicted to be active in mitochondrial outer membrane. Is expressed in adaxial cell; musculature system; nervous system; somite; and trigeminal placode. Orthologous to human VDAC3 (voltage dependent anion channel 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77898 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Eukaryotic porin/Tom40 | Porin domain superfamily | Porin, eukaryotic type |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2BEA2 | InterPro | 319 | |||
| UniProtKB:B0R197 | InterPro | 318 | |||
| UniProtKB:Q6P0S2 | InterPro | 283 | |||
| UniProtKB:A0A8M2BER1 | InterPro | 309 | |||
| UniProtKB:A0A8M2BEA1 | InterPro | 308 |
Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(myl7:GAL4-ECR-2A-vdac3-FLAG,UAS:GFP) |
| 1 | Shimizu et al., 2021 |
1 - 1 of 1
Show
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-220D9 | ZFIN Curated Data | |
| Encodes | EST | fb01e12 | ||
| Encodes | cDNA | MGC:77898 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:174452 | ZFIN Curated Data |
1 - 4 of 4
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213246 (1) | 1560 nt | ||
| Genomic | GenBank:AL954172 (1) | 201525 nt | ||
| Polypeptide | UniProtKB:A0A8M2BEA2 (1) | 319 aa |
- Ren, J., Long, Y., Liu, R., Song, G., Li, Q., Cui, Z. (2021) Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish. International Journal of Molecular Sciences. 22(6):
- Shimizu, H., Huber, S., Langenbacher, A.D., Crisman, L., Huang, J., Wang, K., Wilting, F., Gudermann, T., Schredelseker, J., Chen, J.N. (2021) Glutamate 73 Promotes Anti-arrhythmic Effects of Voltage-Dependent Anion Channel Through Regulation of Mitochondrial Ca2+ Uptake. Frontiers in Physiology. 12:724828
- Faria, M., Prats, E., Gómez-Canela, C., Hsu, C.Y., Arick, M.A., Bedrossiantz, J., Orozco, M., Garcia-Reyero, N., Ziv, T., Ben-Lulu, S., Admon, A., Gómez-Oliván, L.M., Raldúa, D. (2019) Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish. Scientific Reports. 9:16467
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Chen, W.C., Wang, Z., Missinato, M.A., Park, D.W., Long, D.W., Liu, H.J., Zeng, X., Yates, N.A., Kim, K., Wang, Y. (2016) Decellularized zebrafish cardiac extracellular matrix induces mammalian heart regeneration. Science advances. 2:e1600844
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Purushothaman, S., Saxena, S., Meghah, V., Meena Lakshmi, M.G., Singh, S.K., Brahmendra Swamy, C.V., Idris, M.M. (2015) Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress. Journal of sleep research. 24(4):458-65
- Chakravarty, S., Reddy, B.R., Sudhakar, S.R., Saxena, S., Das, T., Meghah, V., Brahmendra Swamy, C.V., Kumar, A., and Idris, M.M. (2013) Chronic Unpredictable Stress (CUS)-Induced Anxiety and Related Mood Disorders in a Zebrafish Model: Altered Brain Proteome Profile Implicates Mitochondrial Dysfunction. PLoS One. 8(5):e63302
- Saxena, S., Singh, S.K., Meena Lakshmi, M.G., Meghah, V., Bhatti, B., Brahmendra Swamy, C.V., Sundaram, C.S., and Idris, M.M. (2012) Proteomic analysis of zebrafish caudal fin regeneration. Molecular & cellular proteomics : MCP. 11(6):M111.014118
- Rösel, T.D., Hung, L.H., Medenbach, J., Donde, K., Starke, S., Benes, V., Rätsch, G., and Bindereif, A. (2011) RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation. The EMBO journal. 30(10):1965-1976
1 - 10 of 11
Show