Gene

pck2

ID
ZDB-GENE-040426-2266
Name
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Symbol
pck2 Nomenclature History
Previous Names
  • id:ibd5157
  • zgc:77867
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; gluconeogenesis; and monocarboxylic acid metabolic process. Predicted to localize to cytosol and mitochondrion. Is expressed in extension; intestinal bulb; liver; and yolk syncytial layer. Orthologous to human PCK2 (phosphoenolpyruvate carboxykinase 2, mitochondrial).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pck2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
PEPCK deficiency, mitochondrial 261650
Associated With pck2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site
Domain IPR035077 Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain
Domain IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal
Family IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising
Homologous_superfamily IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal
Homologous_superfamily IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal
Domain Details Per Protein
Protein Length Phosphoenolpyruvate carboxykinase, C-terminal Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain Phosphoenolpyruvate carboxykinase, GTP-utilising Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal Phosphoenolpyruvate carboxykinase, N-terminal
UniProtKB:F1R9Y5 636
UniProtKB:Q6P3H6 636
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations