Gene
hoga1
- ID
- ZDB-GENE-040426-2242
- Name
- 4-hydroxy-2-oxoglutarate aldolase 1
- Symbol
- hoga1 Nomenclature History
- Previous Names
-
- zgc:77082
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable 4-hydroxy-2-oxoglutarate aldolase activity and N-acetylneuraminate lyase activity. Predicted to be involved in N-acetylneuraminate catabolic process and glyoxylate catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 3. Orthologous to human HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary hyperoxaluria type 3 | Alliance | Hyperoxaluria, primary, type III | 613616 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | DapA-like | Schiff base-forming aldolase, active site |
|---|---|---|---|---|
|
UniProtKB:Q6NY77
|
324 |
Interactions and Pathways
No data available
Plasmids
No data available