Gene

dhdds

ID
ZDB-GENE-040426-2236
Name
dehydrodolichyl diphosphate synthase
Symbol
dhdds Nomenclature History
Previous Names
  • wu:fd56c06
  • zgc:77088 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have dehydrodolichyl diphosphate synthase activity and polyprenyltransferase activity. Involved in detection of light stimulus involved in visual perception and eye photoreceptor cell development. Predicted to localize to dehydrodolichyl diphosphate synthase complex and endoplasmic reticulum. Human ortholog(s) of this gene implicated in developmental delay and seizures with or without movement abnormalities and retinitis pigmentosa 59. Orthologous to human DHDDS (dehydrodolichyl diphosphate synthase subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zuchner et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dhdds Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental delay and seizures with or without movement abnormalities Alliance Developmental delay and seizures with or without movement abnormalities 617836
retinitis pigmentosa 59 Alliance Retinitis pigmentosa 59 613861
retinitis pigmentosa 59 Alliance ?Congenital disorder of glycosylation, type 1bb 613861
Associated With dhdds Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site
Family IPR001441 Decaprenyl diphosphate synthase-like
Homologous_superfamily IPR036424 Decaprenyl diphosphate synthase-like superfamily
Domain Details Per Protein
Protein Length Decaprenyl diphosphate synthase-like Decaprenyl diphosphate synthase-like superfamily Di-trans-poly-cis-decaprenylcistransferase-like, conserved site
UniProtKB:F1R4X6 335
UniProtKB:Q6NXA2 335
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations