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Gene

eif5a

ID
ZDB-GENE-040426-2229
Name
eukaryotic translation initiation factor 5A
Symbol
eif5a Nomenclature History
Previous Names
  • wu:fb17e01
  • wu:fb63h04
  • wu:fk81e04
  • zgc:77099
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable translation elongation factor activity. Predicted to be involved in positive regulation of translational elongation. Predicted to act upstream of or within several processes, including mRNA transport; positive regulation of translational termination; and translation. Predicted to be located in endoplasmic reticulum membrane and nucleus. Predicted to be part of nuclear pore. Is expressed in endoderm; intestine; liver; pancreas; and swim bladder. Orthologous to several human genes including EIF5A (eukaryotic translation initiation factor 5A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif5a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Faundes-Banka syndrome 619376
Associated With eif5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020189 Translation elongation factor, IF5A C-terminal
Family IPR001884 Translation elongation factor IF5A-like
Homologous_superfamily IPR008991 Translation protein SH3-like domain superfamily
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR014722 Ribosomal protein L2, domain 2
PTM IPR019769 Translation elongation factor, IF5A, hypusine site
Domain Details Per Protein
Protein Length Nucleic acid-binding, OB-fold Ribosomal protein L2, domain 2 Translation elongation factor, IF5A C-terminal Translation elongation factor, IF5A, hypusine site Translation elongation factor IF5A-like Translation protein SH3-like domain superfamily
UniProtKB:E9QD54 116
UniProtKB:A7MCI0 135
UniProtKB:Q6NX89 155
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations