Gene

nfkbiaa

ID
ZDB-GENE-040426-2227
Name
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
Symbol
nfkbiaa Nomenclature History
Previous Names
  • ikbaa (1)
  • fj16a07
  • wu:fj16a07
  • zgc:85769 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Involved in negative regulation of hematopoietic progenitor cell differentiation and response to virus. Human ortholog(s) of this gene implicated in hematologic cancer (multiple); hypohidrotic ectodermal dysplasia; lung cancer; melanoma; and prostate cancer. Is expressed in several structures, including lateral line system; periderm; pronephric duct; tail bud; and vent. Orthologous to human NFKBIA (NFKB inhibitor alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from He et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nfkbiaa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ectodermal dysplasia and immunodeficiency 2 612132
Associated With nfkbiaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR020683 Ankyrin repeat-containing domain
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily
UniProtKB:F1QCG4 310
UniProtKB:Q6NUY5 305
UniProtKB:Q6K196 312
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations