Gene
ndufs8a
- ID
- ZDB-GENE-040426-2153
- Name
- NADH:ubiquinone oxidoreductase core subunit S8a
- Symbol
- ndufs8a Nomenclature History
- Previous Names
-
- ndufs8
- wu:fb30b07
- zgc:65835
- zgc:77840 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65835 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 2 | Alliance | Mitochondrial complex I deficiency, nuclear type 2 | 618222 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 4Fe-4S ferredoxin, iron-sulphur binding, conserved site | 4Fe-4S ferredoxin-type, iron-sulphur binding domain | NADH-quinone oxidoreductase, chain I |
|---|---|---|---|---|
|
UniProtKB:Q6P0T0
|
210 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufs8a-201
(1)
|
Ensembl | 1,575 nt |
Interactions and Pathways
No data available
Plasmids
No data available