Gene

ndufs8a

ID
ZDB-GENE-040426-2153
Name
NADH:ubiquinone oxidoreductase core subunit S8a
Symbol
ndufs8a Nomenclature History
Previous Names
  • ndufs8
  • wu:fb30b07
  • zgc:65835
  • zgc:77840 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Is predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndufs8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 2 Alliance Mitochondrial complex I deficiency, nuclear type 2 618222
Associated With ndufs8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
Domain IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain
Family IPR010226 NADH-quinone oxidoreductase, chain I
Domain Details Per Protein
Protein Length 4Fe-4S ferredoxin, iron-sulphur binding, conserved site 4Fe-4S ferredoxin-type, iron-sulphur binding domain NADH-quinone oxidoreductase, chain I
UniProtKB:Q6P0T0 210
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations