Gene
rhoaa
- ID
- ZDB-GENE-040426-2150
- Name
- ras homolog gene family, member Aa
- Symbol
- rhoaa Nomenclature History
- Previous Names
-
- wu:fa66g04
- wu:fb26g07
- zgc:66058
- zgc:85805 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in skeletal muscle satellite cell migration and wound healing, spreading of cells. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Salas-Vidal et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies, somatic mosaic | 618727 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTPase Rho | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6NUX8
|
193 |
Interactions and Pathways
No data available
Plasmids