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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2136
Gene Name: beta-2-microglobulin, like
Gene Symbol: b2ml    Nomenclature History

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Previous Names: wu:fb66f11, wu:fj01f08, zgc:64161

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I and immune response. Predicted to localize to the MHC class I protein complex and extracellular region. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; inflammatory bowel disease; and primary immunodeficiency disease. Is expressed in blastomere and eye. Orthologous to human B2M (beta-2-microglobulin).
Genome Resources: Alliance (1),  Gene:791742 (1),  Ensembl(GRCz11):ENSDARG00000015887 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Blastula:Oblong (3.66h-4.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH b2ml HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH b2ml VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process antigen processing and presentation of peptide antigen via MHC class I (more)
Cellular Component extracellular region (more)
GO Terms (all 5)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA b2ml-202 (1)    Ensembl 3467
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM b2ml No data available
MARKER RELATIONSHIPS
b2ml Contained in: [BAC] DKEY-32E23 (1) (order this)
b2ml Encodes: [EST] fb66f11, fj01f08
[cDNA] MGC:64161 (1) (order this)
b2ml Has Artifact: [EST] fk54g02, fk54g07
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_213126 (1) 3945 bp
Genomic GenBank:CR855300 (1) 173932 bp
Select Tool
Polypeptide UniProtKB:E7F1G6 (1) 116 aa
Sequence Clusters UniGene:77427 (1)
Sequence Information (all 24)
ORTHOLOGY for b2ml ( Chr: 8 )
CITATIONS (21)