Gene

b2ml

ID
ZDB-GENE-040426-2136
Name
beta-2-microglobulin, like
Symbol
b2ml Nomenclature History
Previous Names
  • wu:fb66f11
  • wu:fj01f08
  • zgc:64161
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I and immune response. Predicted to localize to MHC class I protein complex and extracellular region. Is expressed in blastomere and eye. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; immunodeficiency 43; and inflammatory bowel disease. Orthologous to human B2M (beta-2-microglobulin).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With b2ml Human Ortholog
No data available
Associated With b2ml Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Domain IPR003597 Immunoglobulin C1-set
Domain IPR007110 Immunoglobulin-like domain
Family IPR015707 Beta-2-Microglobulin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Beta-2-Microglobulin Immunoglobulin C1-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin/major histocompatibility complex, conserved site
UniProtKB:E7F1G6 116
UniProtKB:Q6PFS6 116
UniProtKB:F1R1W4 95
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations