Gene

gmfb

ID
ZDB-GENE-040426-2114
Name
glia maturation factor, beta
Symbol
gmfb Nomenclature History
Previous Names
  • fc25b01
  • wu:fa97c03
  • wu:fc25b01
  • zgc:56451 (1)
  • zgc:86831
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have Arp2/3 complex binding activity; actin binding activity; and growth factor activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to localize to actin cortical patch. Is expressed in head; hindbrain; and telencephalon. Orthologous to several human genes including GMFB (glia maturation factor beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Yin et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gmfb Human Ortholog
No data available
Associated With gmfb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002108 Actin-depolymerising factor homology domain
Family IPR011171 Glia maturation factor
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Domain Details Per Protein
Protein Length Actin-depolymerising factor homology domain ADF-H/Gelsolin-like domain superfamily Glia maturation factor
UniProtKB:Q7ZUD3 142
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gmfb-201 (1) Ensembl 2,063 nt
ncRNA gmfb-002 (1) Ensembl 797 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations