Gene

hacl1

ID
ZDB-GENE-040426-2058
Name
2-hydroxyacyl-CoA lyase 1
Symbol
hacl1 Nomenclature History
Previous Names
  • phyh2 (1)
  • wu:fd42e11
  • zgc:76920 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have carbon-carbon lyase activity and thiamine pyrophosphate binding activity. Predicted to be involved in fatty acid alpha-oxidation. Predicted to localize to peroxisome. Orthologous to human HACL1 (2-hydroxyacyl-CoA lyase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hacl1 Human Ortholog
No data available
Associated With hacl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding
Domain IPR012000 Thiamine pyrophosphate enzyme, central domain
Domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
Homologous_superfamily IPR029035 DHS-like NAD/FAD-binding domain superfamily
Homologous_superfamily IPR029061 Thiamin diphosphate-binding fold
Domain Details Per Protein
Protein Length DHS-like NAD/FAD-binding domain superfamily Thiamin diphosphate-binding fold Thiamine pyrophosphate enzyme, central domain Thiamine pyrophosphate enzyme, C-terminal TPP-binding Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
UniProtKB:Q6NYI5 568
UniProtKB:F8W559 71
UniProtKB:F1RB36 568
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations