Gene

tcirg1b

ID
ZDB-GENE-040426-2022
Name
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
Symbol
tcirg1b Nomenclature History
Previous Names
  • wu:fb44e06
  • wu:fi46h07
  • zgc:55891
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in vacuolar acidification. Predicted to localize to plasma membrane and vacuolar proton-transporting V-type ATPase complex. Is expressed in macrophage and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tcirg1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive osteopetrosis 1 Alliance Osteopetrosis, autosomal recessive 1 259700
Associated With tcirg1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002490 V-type ATPase, V0 complex, 116kDa subunit family
Family IPR026028 ATPase, V0 complex, subunit 116kDa, eukaryotic
Domain Details Per Protein
Protein Length ATPase, V0 complex, subunit 116kDa, eukaryotic V-type ATPase, V0 complex, 116kDa subunit family
UniProtKB:Q7ZVM7 822
UniProtKB:F1QW04 821
UniProtKB:A0A0R4IJM6 123
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations