ZFIN is now using GRCz12tu for Genomic Data
Gene
tcirg1b
- ID
- ZDB-GENE-040426-2022
- Name
- T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
- Symbol
- tcirg1b Nomenclature History
- Previous Names
-
- wu:fb44e06
- wu:fi46h07
- zgc:55891
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATPase binding activity. Predicted to be involved in vacuolar acidification. Predicted to act upstream of or within proton transmembrane transport. Predicted to be located in membrane. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Predicted to be active in plasma membrane. Is expressed in macrophage and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55891 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive osteopetrosis 1 | Alliance | Osteopetrosis, autosomal recessive 1 | 259700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ATPase, V0 complex, subunit 116kDa, eukaryotic | V-type ATPase, V0 complex, 116kDa subunit family |
|---|---|---|---|---|
| UniProtKB:Q7ZVM7 | InterPro | 822 | ||
| UniProtKB:A0AB32T493 | InterPro | 821 | ||
| UniProtKB:A0AB32T767 | InterPro | 820 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tcirg1b-201
(1)
|
Ensembl | 2,475 nt | ||
| mRNA |
tcirg1b-202
(1)
|
Ensembl | 523 nt | ||
| mRNA |
tcirg1b-204
(1)
|
Ensembl | 3,373 nt | ||
| ncRNA |
tcirg1b-002
(1)
|
Ensembl | 773 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers