Gene
hk2
- ID
- ZDB-GENE-040426-2017
- Name
- hexokinase 2
- Symbol
- hk2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in several processes, including cellular glucose homeostasis; glucose 6-phosphate metabolic process; and phosphorylation. Predicted to act upstream of or within carbohydrate metabolic process and phosphorylation. Predicted to be located in membrane. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; hatching gland; musculature system; and nervous system. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (hexokinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55926 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ATPase, nucleotide binding domain | Hexokinase | Hexokinase, binding site | Hexokinase, C-terminal | Hexokinase, N-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVL7
|
919 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available