Gene
chia.2
- ID
- ZDB-GENE-040426-2014
- Name
- chitinase, acidic.2
- Symbol
- chia.2 Nomenclature History
- Previous Names
-
- chia2 (1)
- wu:fb61c11
- zgc:55941
- zgc:77889
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to localize to cytoplasm and extracellular region. Human ortholog(s) of this gene implicated in asthma and schizophrenia. Is expressed in gut and liver. Orthologous to several human genes including CHIT1 (chitinase 1); CHIA (chitinase acidic); and OVGP1 (oviductal glycoprotein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR001579 | Glycosyl hydrolase family 18, active site |
| Domain | IPR001223 | Glycoside hydrolase family 18, catalytic domain |
| Domain | IPR002557 | Chitin binding domain |
| Family | IPR050314 | Glycosyl Hydrolase Family 18 |
| Homologous_superfamily | IPR017853 | Glycoside hydrolase superfamily |
| Homologous_superfamily | IPR029070 | Chitinase insertion domain superfamily |
| Homologous_superfamily | IPR036508 | Chitin binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Chitinase insertion domain superfamily | Chitin binding domain | Chitin binding domain superfamily | Glycoside hydrolase family 18, catalytic domain | Glycoside hydrolase superfamily | Glycosyl Hydrolase Family 18 | Glycosyl hydrolase family 18, active site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6P006
|
470 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available