Gene
pik3r3a
- ID
- ZDB-GENE-040426-1978
- Name
- phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
- Symbol
- pik3r3a Nomenclature History
- Previous Names
-
- wu:fb16a12
- wu:fk56b03
- zgc:73230
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA. Human ortholog(s) of this gene implicated in colon adenocarcinoma. Orthologous to human PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73230 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PI3K p85 subunit, C-terminal SH2 domain | SH2 domain | SH2 domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:A0A0R4IUJ2 | InterPro | 333 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pik3r3a-201
(1)
|
Ensembl | 2,054 nt | ||
| mRNA |
pik3r3a-203
(1)
|
Ensembl | 2,194 nt | ||
| mRNA |
pik3r3a-204
(1)
|
Ensembl | 3,354 nt | ||
| ncRNA |
pik3r3a-002
(1)
|
Ensembl | 923 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-179O8 | ZFIN Curated Data | |
| Encodes | EST | fb16a12 | ZFIN Curated Data | |
| Encodes | EST | fk56b03 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:73230 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213038 (1) | 3354 nt | ||
| Genomic | GenBank:FP102774 (2) | 37107 nt | ||
| Polypeptide | UniProtKB:A0A0R4IUJ2 (1) | 333 aa |
- Tingaud-Sequeira, A., Trimouille, A., Marlin, S., Lopez, E., Berenguer, M., Gherbi, S., Arveiler, B., Lacombe, D., Rooryck, C. (2020) Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS. Molecular genetics & genomic medicine. 8(10):e1375
- Lin, J.B., Wu, H., Liu, Y.L., Shaw, P.C., Li, P.B. (2018) Transcriptome analysis reveals functional roles of nacreous protein N16 in prednisolone-induced osteoporotic zebrafish. International journal of biological macromolecules. 122:1071-1079
- Li, C., Chen, Q., Zhang, X., Snyder, S.A., Gong, Z., Lam, S.H. (2017) An integrated approach with the zebrafish model for biomonitoring of municipal wastewater effluent and receiving waters. Water research. 131:33-44
- Li, F., Wang, H., Liu, J., Lin, J., Zeng, A., Ai, W., Wang, X., Dahlgren, R.A., Wang, H. (2016) Immunotoxicity of β-Diketone Antibiotic Mixtures to Zebrafish (Danio rerio) by Transcriptome Analysis. PLoS One. 11:e0152530
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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