Gene
rnf185
- ID
- ZDB-GENE-040426-1977
- Name
- ring finger protein 185
- Symbol
- rnf185 Nomenclature History
- Previous Names
-
- zgc:73070 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity and ubiquitin-like protein conjugating enzyme binding activity. Predicted to be involved in several processes, including positive regulation of type I interferon-mediated signaling pathway; protein K27-linked ubiquitination; and proteolysis involved in protein catabolic process. Predicted to act upstream of or within autophagy and innate immune response. Predicted to be located in endoplasmic reticulum membrane and mitochondrial outer membrane. Is expressed in olfactory placode and peripheral olfactory organ. Orthologous to human RNF185 (ring finger protein 185).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73070 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | E3 ubiquitin-protein ligase RNF5/RNF185-like | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6PC78
|
194 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rnf185-202
(1)
|
Ensembl | 933 nt | ||
| mRNA |
rnf185-201
(1)
|
Ensembl | 952 nt | ||
| ncRNA |
rnf185-002
(1)
|
Ensembl | 334 nt |
Interactions and Pathways
No data available
Plasmids
No data available