Gene

katnb1

ID
ZDB-GENE-040426-1954
Name
katanin p80 (WD repeat containing) subunit B 1
Symbol
katnb1 Nomenclature History
Previous Names
  • wu:fj32f02
  • wu:fj65h01 (1)
  • zgc:56071
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable microtubule binding activity. Acts upstream of or within midbrain development. Predicted to be located in cytoplasm and spindle pole. Predicted to be part of katanin complex. Is expressed in brain and pectoral fin. Human ortholog(s) of this gene implicated in lissencephaly 6. Orthologous to human KATNB1 (katanin regulatory subunit B1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With katnb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
lissencephaly 6 Alliance Lissencephaly 6, with microcephaly 616212
Associated With katnb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR017986 WD40-repeat-containing domain
Domain IPR028021 Katanin p80 subunit, C-terminal
Family IPR026962 Katanin p80 WD40 repeat-containing subunit B1
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein beta WD-40 repeat Katanin p80 subunit, C-terminal Katanin p80 WD40 repeat-containing subunit B1 WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A1L1QZA4 163
UniProtKB:Q7ZUV2 694
UniProtKB:A0A1L1QZG7 145
UniProtKB:A0A2U3TW31 694
UniProtKB:E7F7R3 633
UniProtKB:A0A1L1QZF5 247
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations