Gene

acadm

ID
ZDB-GENE-040426-1945
Name
acyl-CoA dehydrogenase medium chain
Symbol
acadm Nomenclature History
Previous Names
  • MCAD (1)
  • fb53e01 (1)
  • wu:fb53e01 (1)
  • zgc:111905
  • zgc:56101 (1)
  • zgc:76911 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have medium-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation and medium-chain fatty acid catabolic process. Predicted to localize to mitochondrion. Is expressed in female organism. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADM (acyl-CoA dehydrogenase medium chain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acadm Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
medium chain acyl-CoA dehydrogenase deficiency Alliance Acyl-CoA dehydrogenase, medium chain, deficiency of 201450
Associated With acadm Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006089 Acyl-CoA dehydrogenase, conserved site
Domain IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
Domain IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
Domain IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
Family IPR034180 Medium-chain specific acyl-CoA dehydrogenase
Homologous_superfamily IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Homologous_superfamily IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
Homologous_superfamily IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA dehydrogenase, conserved site Acyl-CoA dehydrogenase-like, C-terminal Acyl-CoA dehydrogenase/oxidase C-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily Acyl-CoA oxidase/dehydrogenase, central domain Medium-chain specific acyl-CoA dehydrogenase
UniProtKB:B2GT87 424
UniProtKB:A9JTB3 424
UniProtKB:Q6NYM4 424
UniProtKB:Q7ZTH8 424
UniProtKB:Q502R3 424
UniProtKB:A2CG95 426
UniProtKB:A2CG94 247
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations