etfb

ID

ZDB-GENE-040426-1931

Name

electron transfer flavoprotein subunit beta

Symbol

etfb Nomenclature History

Previous Names

wu:fa96b05
wu:fb02d07
wu:fb18b10
zgc:56177

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable electron transfer activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in mitochondrial matrix. Predicted to be part of electron transfer flavoprotein complex. Predicted to be active in mitochondrion. Is expressed in cardiac ventricle. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFB (electron transfer flavoprotein subunit beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56177 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With etfb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
multiple acyl-CoA dehydrogenase deficiency	Alliance	Glutaric acidemia IIB	231680

Associated With etfb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000049	Electron transfer flavoprotein, beta-subunit, conserved site
Domain	IPR014730	Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
Domain	IPR033948	Electron transfer flavoprotein, beta subunit, N-terminal
Family	IPR012255	Electron transfer flavoprotein, beta subunit
Homologous_superfamily	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold