Gene

hnrnph1

ID

ZDB-GENE-040426-1856

Name

heterogeneous nuclear ribonucleoprotein H1

Symbol

hnrnph1 Nomenclature History

Previous Names

zgc:77712

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in Sjogren's syndrome and syndromic X-linked intellectual disability. Orthologous to several human genes including HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77712 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hnrnph1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects	620083

Associated With hnrnph1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR012996	Zinc finger, CHHC-type
Family	IPR050666	Epithelial Splicing Regulatory
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Epithelial Splicing Regulatory	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain	Zinc finger, CHHC-type
UniProtKB:Q6P0V0 InterPro	403
UniProtKB:A0A8M9QKJ1 InterPro	375
UniProtKB:A0A8M2BGX3 InterPro	240
UniProtKB:A0A8M2BGZ6 InterPro	377
UniProtKB:A0A0R4IZE3 InterPro	402
UniProtKB:A0A8M2BGV0 InterPro	400