Gene

irx4a

ID
ZDB-GENE-040426-1825
Name
iroquois homeobox 4a
Symbol
irx4a Nomenclature History
Previous Names
  • ziro4a (1)
  • zgc:77362 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in photoreceptor cell development; posterior lateral line neuromast hair cell differentiation; and posterior lateral line neuromast mantle cell differentiation. Predicted to localize to nucleus. Is expressed in several structures, including midbrain neural keel; nervous system; neural plate; pericardial region; and presumptive neural retina. Orthologous to human IRX4 (iroquois homeobox 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Feijoo et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With irx4a Human Ortholog
No data available
Associated With irx4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR003893 Iroquois-class homeodomain protein
Domain IPR008422 KN homeodomain
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain Iroquois-class homeodomain protein KN homeodomain
UniProtKB:Q6NZU4 440
UniProtKB:A0A8M9PJE4 441
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA irx4a-201 (1) Ensembl 2,067 nt
ncRNA irx4a-002 (1) Ensembl 938 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations