Gene

dpm3

ID
ZDB-GENE-040426-1782
Name
dolichyl-phosphate mannosyltransferase subunit 3, regulatory
Symbol
dpm3 Nomenclature History
Previous Names
  • zgc:73376 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to contribute to dolichyl-phosphate beta-D-mannosyltransferase activity. Involved in muscle structure development. Predicted to localize to dolichol-phosphate-mannose synthase complex and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation. Is expressed in brain; cloaca; pronephric duct; solid lens vesicle; and vertical myoseptum. Orthologous to human DPM3 (dolichyl-phosphate mannosyltransferase subunit 3, regulatory).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Marchese et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dpm3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
muscular dystrophy-dystroglycanopathy type B15 Alliance ?Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type B, 15 618992
Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 15 612937
Associated With dpm3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR013174 Dolichol-phosphate mannosyltransferase subunit 3
Domain Details Per Protein
Protein Length Dolichol-phosphate mannosyltransferase subunit 3
UniProtKB:Q1LXA2 92
UniProtKB:Q6PBJ5 92
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations