Gene
pam16
- ID
- ZDB-GENE-040426-1776
- Name
- presequence translocase associated motor 16
- Symbol
- pam16 Nomenclature History
- Previous Names
-
- zgc:73356
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be involved in protein import into mitochondrial matrix. Predicted to act upstream of or within protein transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Orthologous to human PAM16 (presequence translocase associated motor 16).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73356 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondylometaphyseal dysplasia Megarbane-Dagher-Melike type | Alliance | Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type | 613320 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chaperone J-domain superfamily | Mitochondrial import inner membrane translocase subunit Tim16 |
|---|---|---|---|
|
UniProtKB:A0A0R4IJF5
|
129 | ||
|
UniProtKB:Q6PBL0
|
129 |
Interactions and Pathways
No data available
Plasmids
No data available