Gene

clu

ID
ZDB-GENE-040426-1774
Name
clusterin
Symbol
clu Nomenclature History
Previous Names
  • zgc:73352
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have misfolded protein binding activity. Involved in regulation of neuron death. Predicted to localize to extracellular space and nucleus. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; diabetic retinopathy; exfoliation syndrome; and muscular disease (multiple). Is expressed in several structures, including digestive system; male organism; nervous system; notochord; and pleuroperitoneal region. Orthologous to human CLU (clusterin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Jeong et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With clu Human Ortholog
No data available
Associated With clu Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR016014 Clusterin, N-terminal
Domain IPR016015 Clusterin, C-terminal
Family IPR000753 Clusterin-like
Family IPR016016 Clusterin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations