ZFIN ID: ZDB-GENE-040426-1758
Gene Name: cyclase associated actin cytoskeleton regulatory protein 2
Gene Symbol: cap2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: zgc:113089, zgc:73317

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have actin binding activity and adenylate cyclase binding activity. Predicted to be involved in actin polymerization or depolymerization; cell morphogenesis; and establishment or maintenance of cell polarity. Predicted to localize to the cortical actin cytoskeleton. Is expressed in central nervous system; heart; male organism; muscle; and neural tube. Orthologous to human CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).
Genome Resources: Alliance (1),  Gene:393809 (1),  Ensembl(GRCz11):ENSDARG00000104478 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32263 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cap2 N/A 1
    MO2-cap2 N/A 1
    PHENOTYPE
    Data: Fig. 2 from Effendi et al., 2013
    Observed in:
    DISEASE ASSOCIATED WITH cap2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cap2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell morphogenesis (more)
    Cellular Component cortical actin cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001837 Adenylate cyclase-associated CAP
    Domain IPR006599 CARP motif
    Domain IPR013912 Adenylate cyclase-associated CAP, C-terminal
    Domain IPR013992 Adenylate cyclase-associated CAP, N-terminal
    Homologous_superfamily IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal
    Domain IPR017901 C-CAP/cofactor C-like domain
    Conserved_site IPR018106 CAP, conserved site, N-terminal
    Conserved_site IPR028417 CAP, conserved site, C-terminal
    Homologous_superfamily IPR036222 Adenylate cyclase-associated CAP, N-terminal domain superfamily
    Homologous_superfamily IPR036223 Adenylate cyclase-associated CAP, C-terminal superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cap2-202 (1)    Ensembl 3214
    ncRNA cap2-002 (1)    Ensembl 615
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cap2 No data available
    MARKER RELATIONSHIPS
    cap2 Contained in: [Fosmid] CH1073-175O15 (1), CH1073-228H2 (1), CH1073-243K12 (1)
    cap2 Encodes: [cDNA] MGC:73317 (1), MGC:113089 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200836 (1) 3122 bp
    Genomic GenBank:CU856142 (1) 31900 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IXA9 (1) 468 aa
    Sequence Information (all 20)
    ORTHOLOGY for cap2 ( Chr: 19 )
    CITATIONS (16)