Gene
chchd2
- ID
- ZDB-GENE-040426-1737
- Name
- coiled-coil-helix-coiled-coil-helix domain containing 2
- Symbol
- chchd2 Nomenclature History
- Previous Names
-
- chchd2l
- zgc:73266 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have sequence-specific DNA binding activity. Predicted to be involved in mitochondrion organization and positive regulation of transcription by RNA polymerase II. Predicted to localize to mitochondrion and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease 22. Orthologous to human CHCHD2 (coiled-coil-helix-coiled-coil-helix domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Babu et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Parkinson's disease 22 | Alliance | Parkinson disease 22, autosomal dominant | 616710 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010625 | CHCH |
Domain Details Per Protein
| Protein | Length | CHCH |
|---|---|---|
|
UniProtKB:Q6PBS8
|
168 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
chchd2-201
(1)
|
Ensembl | 961 nt | ||
| mRNA |
chchd2-202
(1)
|
Ensembl | 713 nt |
Interactions and Pathways
No data available
Plasmids
No data available