Gene

pyroxd1

ID
ZDB-GENE-040426-1732
Name
pyridine nucleotide-disulphide oxidoreductase domain 1
Symbol
pyroxd1 Nomenclature History
Previous Names
  • ryroxd1 (1)
  • zgc:73254
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to nucleus and sarcomere. Human ortholog(s) of this gene implicated in myofibrillar myopathy 8. Is expressed in female organism and trunk musculature. Orthologous to human PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from O'Grady et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pyroxd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myofibrillar myopathy 8 Alliance Myopathy, myofibrillar, 8 617258
Associated With pyroxd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR023753 FAD/NAD(P)-binding domain
Domain IPR041575 NADH-rubredoxin oxidoreductase, C-terminal
Homologous_superfamily IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily
Homologous_superfamily IPR036188 FAD/NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length FAD/NAD-linked reductase, dimerisation domain superfamily FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain superfamily NADH-rubredoxin oxidoreductase, C-terminal
UniProtKB:Q6PBT5 490
UniProtKB:A0A0R4IEM7 485
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ryroxd1
  • WB
Abmart
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations