ZFIN is now using GRCz12tu for Genomic Data

Gene

arhgap12b

ID

ZDB-GENE-040426-1727

Name

Rho GTPase activating protein 12b

Symbol

arhgap12b Nomenclature History

Previous Names

arhgap12
zgc:73239 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GTPase activator activity. Predicted to be involved in small GTPase-mediated signal transduction. Predicted to be active in cytoplasm and plasma membrane. Is expressed in retina and somite. Orthologous to human ARHGAP12 (Rho GTPase activating protein 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7151471 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgap12b Human Ortholog

No data available

Associated With arhgap12b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001202	WW domain
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR035491	ARHGAP12, SH3 domain
Family	IPR050729	Rho GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036020	WW domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A0R4IKK1	InterPro	841
UniProtKB:A0A8M9QME4	InterPro	882
UniProtKB:A0A8M9QIL2	InterPro	881
UniProtKB:A0A8M9QE56	InterPro	458
UniProtKB:A0A8M9Q893	InterPro	664
UniProtKB:Q6P4P5	InterPro	817
UniProtKB:A0A8M9PW53	InterPro	858
UniProtKB:A0AB32U447	InterPro	882
UniProtKB:A0AC58GV32	InterPro	851
UniProtKB:A0AC58GV33	InterPro	857
UniProtKB:A0AC58GV34	InterPro	816
UniProtKB:A0AC58GV35	InterPro	841
UniProtKB:A0AC58GV36	InterPro	840
UniProtKB:A0AC58GV37	InterPro	893
UniProtKB:A0AC58GV38	InterPro	840
UniProtKB:A0AC58GV41	InterPro	675
UniProtKB:A0AC58GV42	InterPro	664
UniProtKB:A0AC58GV44	InterPro	663
UniProtKB:A0AC58GV45	InterPro	852
UniProtKB:A0AC58GV46	InterPro	892
UniProtKB:A0AC58GV47	InterPro	623
UniProtKB:A0AC58GV48	InterPro	503
UniProtKB:A0AC58GV49	InterPro	502
UniProtKB:A0AC58GV50	InterPro	501
UniProtKB:A0AC58GV51	InterPro	544
UniProtKB:A0AC58GV52	InterPro	526
UniProtKB:A0AC58GV53	InterPro	623
UniProtKB:A0AC58GV54	InterPro	640
UniProtKB:A0AC58GV55	InterPro	527
UniProtKB:A0AC58GV56	InterPro	599
UniProtKB:A0AC58GV57	InterPro	598
UniProtKB:A0AC58GV58	InterPro	527
UniProtKB:A0AC58GV59	InterPro	500
UniProtKB:A0AC58GV60	InterPro	634
UniProtKB:A0AC58GV62	InterPro	622
UniProtKB:A0AC58GV64	InterPro	459
UniProtKB:A0AC58GV67	InterPro	477
UniProtKB:A0AC58GV69	InterPro	460
UniProtKB:A0AC58GV75	InterPro	471
UniProtKB:A0AC58GV85	InterPro	436

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arhgap12b-201 (1) Ensembl	Ensembl	4,227 nt	Select Tool ZFIN BLAST
mRNA	arhgap12b-202 (1) Ensembl	Ensembl	831 nt	Select Tool ZFIN BLAST
mRNA	arhgap12b-203 (1) Ensembl	Ensembl	463 nt	Select Tool ZFIN BLAST
mRNA	arhgap12b-204 (1) Ensembl	Ensembl	4,670 nt	Select Tool ZFIN BLAST
mRNA	arhgap12b-205 (1) Ensembl	Ensembl	4,617 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations