Gene
arhgap12b
- ID
- ZDB-GENE-040426-1727
- Name
- Rho GTPase activating protein 12b
- Symbol
- arhgap12b Nomenclature History
- Previous Names
-
- arhgap12
- zgc:73239 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in small GTPase-mediated signal transduction. Predicted to be active in cytoplasm and plasma membrane. Is expressed in retina and somite. Orthologous to human ARHGAP12 (Rho GTPase activating protein 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151471 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000198 | Rho GTPase-activating protein domain |
| Domain | IPR001202 | WW domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR035491 | ARHGAP12, SH3 domain |
| Family | IPR050729 | Rho GTPase-activating protein |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036020 | WW domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | ARHGAP12, SH3 domain | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating protein | Rho GTPase-activating protein domain | Rho GTPase activation protein | SH3 domain | SH3-like domain superfamily | WW domain | WW domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IKK1 | InterPro | 841 | ||||||||||
| UniProtKB:A0A8M9QME4 | InterPro | 882 | ||||||||||
| UniProtKB:A0A8M9QIL2 | InterPro | 881 | ||||||||||
| UniProtKB:A0A8M9QE56 | InterPro | 458 | ||||||||||
| UniProtKB:A0A8M9Q893 | InterPro | 664 | ||||||||||
| UniProtKB:Q6P4P5 | InterPro | 817 | ||||||||||
| UniProtKB:A0A8M9PW53 | InterPro | 858 | ||||||||||
| UniProtKB:A0AB32U447 | InterPro | 882 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgap12b-201
(1)
|
Ensembl | 4,227 nt | ||
| mRNA |
arhgap12b-202
(1)
|
Ensembl | 831 nt | ||
| mRNA |
arhgap12b-203
(1)
|
Ensembl | 463 nt | ||
| mRNA |
arhgap12b-204
(1)
|
Ensembl | 4,670 nt | ||
| mRNA |
arhgap12b-205
(1)
|
Ensembl | 4,617 nt |
Interactions and Pathways
No data available
Plasmids
No data available