Gene

exosc4

ID
ZDB-GENE-040426-1702
Name
exosome component 4
Symbol
exosc4 Nomenclature History
Previous Names
  • exosome complex exonuclease RRP41 (1)
  • zgc:73175
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have exonuclease activity. Predicted to be involved in RNA metabolic process. Predicted to localize to cytoplasmic exosome (RNase complex); nuclear exosome (RNase complex); and nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; midbrain; pectoral fin bud; and segmental plate. Orthologous to human EXOSC4 (exosome component 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With exosc4 Human Ortholog
No data available
Associated With exosc4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001247 Exoribonuclease, phosphorolytic domain 1
Domain IPR015847 Exoribonuclease, phosphorolytic domain 2
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR027408 PNPase/RNase PH domain superfamily
Homologous_superfamily IPR036345 Exoribonuclease, PH domain 2 superfamily
Domain Details Per Protein
Protein Length Exoribonuclease, PH domain 2 superfamily Exoribonuclease, phosphorolytic domain 1 Exoribonuclease, phosphorolytic domain 2 PNPase/RNase PH domain superfamily Ribosomal protein S5 domain 2-type fold
UniProtKB:A0A0R4IV90 241
UniProtKB:Q6PBZ8 245
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations