Gene
exosc4
- ID
- ZDB-GENE-040426-1702
- Name
- exosome component 4
- Symbol
- exosc4 Nomenclature History
- Previous Names
-
- exosome complex exonuclease RRP41 (1)
- zgc:73175
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have exonuclease activity. Predicted to be involved in RNA metabolic process. Predicted to localize to cytoplasmic exosome (RNase complex); nuclear exosome (RNase complex); and nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; midbrain; pectoral fin bud; and segmental plate. Orthologous to human EXOSC4 (exosome component 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73175 (15 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001247 | Exoribonuclease, phosphorolytic domain 1 |
| Domain | IPR015847 | Exoribonuclease, phosphorolytic domain 2 |
| Family | IPR050080 | Ribonuclease PH |
| Homologous_superfamily | IPR020568 | Ribosomal protein uS5 domain 2-type superfamily |
| Homologous_superfamily | IPR027408 | PNPase/RNase PH domain superfamily |
| Homologous_superfamily | IPR036345 | Exoribonuclease, PH domain 2 superfamily |
Domain Details Per Protein
| Protein | Length | Exoribonuclease, PH domain 2 superfamily | Exoribonuclease, phosphorolytic domain 1 | Exoribonuclease, phosphorolytic domain 2 | PNPase/RNase PH domain superfamily | Ribonuclease PH | Ribosomal protein uS5 domain 2-type superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6PBZ8
|
245 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
exosc4-201
(1)
|
Ensembl | 782 nt |
Interactions and Pathways
No data available
Plasmids
No data available