Gene
ndufa8
- ID
- ZDB-GENE-040426-1688
- Name
- NADH:ubiquinone oxidoreductase subunit A8
- Symbol
- ndufa8 Nomenclature History
- Previous Names
-
- zgc:73139 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; liver; optic tectum; optic vesicle; and retina. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to human NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73139 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mitochondrial complex I deficiency, nuclear type 37 | 619272 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR016680 | NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 |
|---|---|---|
|
UniProtKB:Q6PC22
|
172 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufa8-201
(1)
|
Ensembl | 805 nt |
Interactions and Pathways
No data available
Plasmids
No data available