Gene

cib2

ID
ZDB-GENE-040426-1663
Name
calcium and integrin binding family member 2
Symbol
cib2 Nomenclature History
Previous Names
  • zgc:73079
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in camera-type eye development; mechanosensory behavior; and neuromast development. Is expressed in central nervous system and cranial ganglion. Human ortholog(s) of this gene implicated in Usher syndrome type 1J and autosomal recessive nonsyndromic deafness 48. Orthologous to human CIB2 (calcium and integrin binding family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Riazuddin et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cib2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 48 Alliance Deafness, autosomal recessive 48 609439
Usher syndrome type 1J Alliance Usher syndrome, type IJ 614869
Associated With cib2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair
UniProtKB:Q6PC72 187
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations