Gene
fbxo43
- ID
- ZDB-GENE-040426-1645
- Name
- F-box protein 43
- Symbol
- fbxo43 Nomenclature History
- Previous Names
-
- zgc:66488
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in negative regulation of meiotic nuclear division and regulation of mitotic nuclear division. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spermatogenic failure 64. Orthologous to human FBXO43 (F-box protein 43).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:113982 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 64 | Alliance | Spermatogenic failure 64 | 619696 |
| Oocyte/zygote/embryo maturation arrest 12 | 619697 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | F-box only protein 5/43 | Zinc finger ZBR-type domain |
|---|---|---|---|
|
UniProtKB:Q7SYI4
|
557 | ||
|
UniProtKB:F1QE49
|
557 | ||
|
UniProtKB:A0A8M9PJC1
|
505 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fbxo43-201
(1)
|
Ensembl | 2,094 nt | ||
| mRNA |
fbxo43-202
(1)
|
Ensembl | 2,101 nt |
Interactions and Pathways
No data available
Plasmids
No data available