Gene
timm50
- ID
- ZDB-GENE-040426-1618
- Name
- translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
- Symbol
- timm50 Nomenclature History
- Previous Names
-
- zgc:66357 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Acts upstream of or within apoptotic process. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in several structures, including immature eye; margin; midbrain; pectoral fin musculature; and segmental plate. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66357 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 3-methylglutaconic aciduria type 9 | Alliance | 3-methylglutaconic aciduria, type IX | 617698 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | FCP1 homology domain | HAD-like superfamily | HAD superfamily | Mitochondrial import inner membrane translocase subunit TIM50 |
|---|---|---|---|---|---|
|
UniProtKB:Q6NWD4
|
387 | ||||
|
UniProtKB:B2GQE9
|
387 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timm50-201
(1)
|
Ensembl | 1,807 nt |
Interactions and Pathways
No data available
Plasmids
No data available