Gene

hibadhb

ID

ZDB-GENE-040426-1582

Name

3-hydroxyisobutyrate dehydrogenase b

Symbol

hibadhb Nomenclature History

Previous Names

hibadh
zgc:66262

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have 3-hydroxyisobutyrate dehydrogenase activity. Predicted to be involved in valine catabolic process. Predicted to localize to mitochondrion. Is expressed in mesenchyme pectoral fin and myoblast. Orthologous to human HIBADH (3-hydroxyisobutyrate dehydrogenase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66262 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hibadhb Human Ortholog

No data available

Associated With hibadhb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002204	3-hydroxyisobutyrate dehydrogenase-related, conserved site
Domain	IPR006115	6-phosphogluconate dehydrogenase, NADP-binding
Domain	IPR029154	3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain
Family	IPR011548	3-hydroxyisobutyrate dehydrogenase
Family	IPR015815	3-hydroxyisobutyrate dehydrogenase-related
Homologous_superfamily	IPR008927	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Homologous_superfamily	IPR013328	6-phosphogluconate dehydrogenase, domain 2
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily

Domain Details Per Protein

Protein	Length	3-hydroxyisobutyrate dehydrogenase	3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain	3-hydroxyisobutyrate dehydrogenase-related	3-hydroxyisobutyrate dehydrogenase-related, conserved site	6-phosphogluconate dehydrogenase, domain 2	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	6-phosphogluconate dehydrogenase, NADP-binding	NAD(P)-binding domain superfamily
UniProtKB:Q7SXJ4 InterPro	329

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hibadhb-201 (1) Ensembl	Ensembl	1,584 nt	Select Tool ZFIN BLAST
ncRNA	hibadhb-002 (1) Ensembl	Ensembl	766 nt	Select Tool ZFIN BLAST
ncRNA	hibadhb-003 (1) Ensembl	Ensembl	642 nt	Select Tool ZFIN BLAST
ncRNA	hibadhb-004 (1) Ensembl	Ensembl	947 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations