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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1552
Gene Name: nedd8 activating enzyme E1 subunit 1
Gene Symbol: nae1
Sequence Ontology ID : SO:0000704

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Previous Names: appbp1, zgc:66148

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have NEDD8 activating enzyme activity; predicted to be involved in protein neddylation; predicted to localize to the cytoplasm; orthologous to human NAE1 (NEDD8 activating enzyme E1  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66148]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138842]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026093Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34155 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40985 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nae1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nae1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein neddylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function NEDD8 activating enzyme activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000594 (1)
  • InterPro:IPR030667 (1)
  • InterPro:IPR035985 (1)
  • Pfam:PF00899 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nae1-201 (1) 1829
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nae1 No data available
    MARKER RELATIONSHIPS
    nae1Contained in: [BAC] DKEY-71E3 (1) (order this)
    nae1Encodes: [EST] IMAGE:7138842 (1) (order this)
    [cDNA] MGC:66148 (1) (order this), MGC:171400 (1) (order this), MGC:198186 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200499 (1) 1843bp
    Genomic GenBank:BX511136 187217bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ICE9 (1) 548aa
    Sequence Clusters UniGene:26720 (1)
    Sequence Information (all 22)
    ORTHOLOGY for nae1 (Chr: 7)
    CITATIONS (24)