Gene

kif4

ID
ZDB-GENE-040426-1545
Name
kinesin family member 4
Symbol
kif4 Nomenclature History
Previous Names
  • zgc:66125 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement and mitotic spindle organization. Predicted to localize to kinesin complex and microtubule. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human KIF4A (kinesin family member 4A) and KIF4B (kinesin family member 4B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kif4 Human Ortholog
No data available
Associated With kif4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019821 Kinesin motor domain, conserved site
Domain IPR001752 Kinesin motor domain
Domain IPR033467 Tesmin/TSO1-like CXC domain
Family IPR027640 Kinesin-like protein
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Kinesin-like protein Kinesin motor domain Kinesin motor domain, conserved site Kinesin motor domain superfamily P-loop containing nucleoside triphosphate hydrolase Tesmin/TSO1-like CXC domain
UniProtKB:Q6P9P4 1248
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kif4-201 (1) Ensembl 5,511 nt
mRNA kif4-203 (1) Ensembl 7,710 nt
ncRNA kif4-002 (1) Ensembl 695 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations