Gene
mboat7
- ID
- ZDB-GENE-040426-1516
- Name
- membrane bound O-acyltransferase domain containing 7
- Symbol
- mboat7 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable O-acyltransferase activity and lysophospholipid acyltransferase activity. Predicted to be involved in glycerophospholipid metabolic process; lipid modification; and regulation of triglyceride metabolic process. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane and mitochondria-associated endoplasmic reticulum membrane contact site. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 57. Orthologous to human MBOAT7 (membrane bound O-acyltransferase domain containing 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149792 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 57 | Alliance | Intellectual developmental disorder, autosomal recessive 57 | 617188 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Lysophospholipid acyltransferase 7/Porcupine-like | Membrane bound O-acyl transferase, MBOAT |
|---|---|---|---|---|
| UniProtKB:Q7SZQ0 | InterPro | 467 | ||
| UniProtKB:F1Q9V3 | InterPro | 467 | ||
| UniProtKB:A0AB32T4N1 | InterPro | 515 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mboat7-201
(1)
|
Ensembl | 2,251 nt |
Interactions and Pathways
No data available
Plasmids
No data available