Gene

krt18b

ID
ZDB-GENE-040426-1508
Name
keratin 18b
Symbol
krt18b Nomenclature History
Previous Names
  • krtt1c6 (1)
  • keratin 18 (1)
  • zgc:66015
  • zgc:77517
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable structural molecule activity. Predicted to be involved in intermediate filament cytoskeleton organization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Is expressed in several structures, including floor plate; sensory system; vein; yolk; and yolk syncytial layer. Human ortholog(s) of this gene implicated in liver cirrhosis and non-alcoholic steatohepatitis. Orthologous to human KRT18 (keratin 18).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With krt18b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cirrhosis, cryptogenic 215600
{Cirrhosis, noncryptogenic, susceptibility to} 215600
Associated With krt18b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR039008 Intermediate filament, rod domain
Family IPR002957 Keratin, type I
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Keratin, type I
UniProtKB:Q6PHE4 405
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA zgc:77517-201 (1) Ensembl 1,827 nt
mRNA zgc:77517-202 (1) Ensembl 1,302 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations