ZFIN ID: ZDB-GENE-040426-1441
Gene Name: protein tyrosine phosphatase non-receptor type 12
Gene Symbol: ptpn12
Sequence Ontology ID : SO:0000704

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Previous Names: zgc:65856, zgc:77437

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein tyrosine phosphatase activity; predicted to be involved in protein dephosphorylation; orthologous to human PTPN12 (protein tyrosine phosphatase, non-receptor type 12).
GENE EXPRESSION
All Expression Data: 6 figures from 2 publications
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [MGC:65856]
  1 figure (1 image) from Thisse et al., 2004 [MGC:77437]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: Fig. 4 from Duffy et al., 2015
Observed in:
DISEASE ASSOCIATED WITH ptpn12 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
colorectal cancer Colon cancer, somatic 114500
DISEASE ASSOCIATED WITH ptpn12 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dephosphorylation (more)
Cellular Component cytoplasm (more)
Molecular Function hydrolase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000242 (1)
  • InterPro:IPR000387 (1)
  • InterPro:IPR003595 (1)
  • InterPro:IPR012266 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR029021 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50055 (1)
  • PROSITE:PS50056 (1)
  • Pfam:PF00102 (1)
  • EC:3.1.3.48 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ptpn12 No data available
    MARKER RELATIONSHIPS
    ptpn12Encodes: [cDNA] MGC:65856 (1) (order this), MGC:77437 (1) (order this), MGC:175047 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200669 (1)
    Genomic GenBank:CABZ01118791 (1) 5027bp
    Polypeptide UniProtKB:Q6NZ14 (1) 572aa
    Sequence Clusters UniGene:84683 (1)
    Sequence Information (all 22)
    OTHER ptpn12 GENE PAGES
  • Alliance (1)
  • Gene:393642 (1)
  • Ensembl(GRCz11):ENSDARG00000102141 (1)
  • ORTHOLOGY for ptpn12 (Chr: 4)
    CITATIONS (16)