ZFIN is now using GRCz12tu for Genomic Data
Gene
bmp5
- ID
- ZDB-GENE-040426-1413
- Name
- bone morphogenetic protein 5
- Symbol
- bmp5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine activity. Involved in enteric nervous system development. Acts upstream of or within neural crest cell development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of SMAD protein signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including intestinal bulb primordium; nervous system; neural crest; optic vesicle; and pharyngeal arch. Orthologous to human BMP5 (bone morphogenetic protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64230 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
| Domain | IPR001111 | TGF-beta, propeptide |
| Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
| Family | IPR015615 | Transforming growth factor-beta-related |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T288 | InterPro | 446 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers