ZFIN ID: ZDB-GENE-040426-1413
Gene Name: bone morphogenetic protein 5
Gene Symbol: bmp5    Nomenclature History

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Previous Names: bmp5l (1), hm:zehl0669 (1), zehl0669, zgc:64230 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have BMP receptor binding activity and cytokine activity. Involved in neural crest cell development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to localize to extracellular space. Is expressed in several structures, including neural crest; optic vesicle; periderm; pharyngeal arch; and sensory system. Orthologous to human BMP5 (bone morphogenetic protein 5).
Genome Resources: Alliance (1),  Gene:394026 (1),  Ensembl(GRCz11):ENSDARG00000101701 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30324 Point Mutation Unknown Premature Stop ENU
sa39497 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45870 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-bmp5 N/A 2
    MO2-bmp5 N/A 1
    DISEASE ASSOCIATED WITH bmp5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bmp5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neural crest cell development (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bmp5 No data available
    MARKER RELATIONSHIPS
    bmp5 Encodes: [EST] zehl0669
    [cDNA] MGC:64230 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201051 (1) 2223 nt
    Genomic GenBank:CABZ01045749 (1) 5577 nt
    Polypeptide UniProtKB:A0A0R4ILD5 (1) 446 aa
    Sequence Information (all 15)
    ORTHOLOGY for bmp5 ( Chr: 13 )
    CITATIONS (33)