Gene

wipi1

ID

ZDB-GENE-040426-1404

Name

WD repeat domain, phosphoinositide interacting 1

Symbol

wipi1 Nomenclature History

Previous Names

zgc:64205 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable phosphatidylinositol-3,5-bisphosphate binding activity; phosphatidylinositol-3-phosphate binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in autophagy of mitochondrion and macroautophagy. Predicted to act upstream of or within autophagy. Predicted to be active in cytosol and phagophore assembly site membrane. Is expressed in central nervous system; notochord; and periderm. Orthologous to human WIPI1 (WD repeat domain, phosphoinositide interacting 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64205 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Wang et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wipi1 Human Ortholog

No data available

Associated With wipi1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR048720	PROPPIN
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat