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ZIRC
ZFIN ID: ZDB-GENE-040426-1375
Gene Name: hydroxymethylbilane synthase a
Gene Symbol: hmbsa
Sequence Ontology ID : SO:0000704

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Previous Names: hmbs, zgc:64128

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have hydroxymethylbilane synthase activity; predicted to be involved in heme biosynthetic process; predicted to localize to the cytoplasm; orthologous to human HMBS (hydroxymethylbilane  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Segmentation:5-9 somites (11.66h-14.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31452 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hmbsa HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute intermittent porphyria Porphyria, acute intermittent 176000
    Porphyria, acute intermittent, nonerythroid variant 176000
    DISEASE ASSOCIATED WITH hmbsa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peptidyl-pyrromethane cofactor linkage (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydroxymethylbilane synthase activity (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hmbsa-201 (1) 1990
    hmbsa-202 (1) 912
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hmbsa No data available
    MARKER RELATIONSHIPS
    hmbsaContained in: [BAC] DKEY-151N15 (1) (order this)
    hmbsaEncodes: [cDNA] MGC:64128 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201154 (1) 2006bp
    Genomic GenBank:BX294169 (1) 73230bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IQ55 (1) 361aa
    Sequence Clusters UniGene:79518 (1)
    Sequence Information (all 14)
    ORTHOLOGY for hmbsa (Chr: 5)
    CITATIONS (27)