Gene

prkacba

ID
ZDB-GENE-040426-1351
Name
protein kinase, cAMP-dependent, catalytic, beta a
Symbol
prkacba Nomenclature History
Previous Names
  • zgc:64054
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable cAMP-dependent protein kinase activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; fin bud; hatching gland; optic cup; and retinal neural layer. Orthologous to human PRKACB (protein kinase cAMP-activated catalytic subunit beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Emerson et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkacba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cardioacrofacial dysplasia 2 619143
1 - 1 of 1
Associated With prkacba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Family IPR044109 cAMP-dependent protein kinase catalytic subunit
1 - 5 of 6 Show all
Domain Details Per Protein
Protein Additional Resources Length AGC-kinase, C-terminal cAMP-dependent protein kinase catalytic subunit Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q7T374 InterPro 395
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prkacba-201 (1) Ensembl 2,483 nt
mRNA prkacba-202 (1) Ensembl 1,458 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations