Gene
prkacba
- ID
- ZDB-GENE-040426-1351
- Name
- protein kinase, cAMP-dependent, catalytic, beta a
- Symbol
- prkacba Nomenclature History
- Previous Names
-
- zgc:64054
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable cAMP-dependent protein kinase activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; fin bud; hatching gland; optic cup; and retinal neural layer. Orthologous to human PRKACB (protein kinase cAMP-activated catalytic subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Emerson et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cardioacrofacial dysplasia 2 | 619143 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Family | IPR044109 | cAMP-dependent protein kinase catalytic subunit |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | AGC-kinase, C-terminal | cAMP-dependent protein kinase catalytic subunit | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T374 | InterPro | 395 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prkacba-201
(1)
|
Ensembl | 2,483 nt | ||
| mRNA |
prkacba-202
(1)
|
Ensembl | 1,458 nt |
Interactions and Pathways
No data available
Plasmids
No data available