Gene

bokb

ID
ZDB-GENE-040426-1346
Name
BCL2 family apoptosis regulator BOK b
Symbol
bokb Nomenclature History
Previous Names
  • zBok2 (1)
  • zgc:64041
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable channel activity. Predicted to act upstream of or within apoptotic process and regulation of apoptotic process. Predicted to be located in membrane. Predicted to be active in mitochondrial outer membrane. Is expressed in several structures, including chordo neural hinge; nervous system; neural tube; ovary; and solid lens vesicle. Orthologous to human BOK (BCL2 family apoptosis regulator BOK).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa13282Allele with one point mutationUnknownPremature StopENU
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-bokb
    (2)
    CRISPR2-bokb
      (2)
      1 - 2 of 2
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      Human Disease
      Associated With bokb Human Ortholog
      No data available
      Associated With bokb Via Experimental Models
      No data available
      Gene Ontology
      Protein Domains
      Domain, Family, and Site Summary
      Type InterPro ID Name
      Domain IPR003093 Apoptosis regulator, Bcl-2 protein, BH4
      Domain IPR046371 Bcl-2, Bcl-2 homology region 1-3
      Family IPR002475 Bcl2-like
      Family IPR026298 Bcl-2 family
      Homologous_superfamily IPR036834 Bcl-2-like superfamily
      1 - 5 of 5
      Domain Details Per Protein
      Protein Additional Resources Length Apoptosis regulator, Bcl-2 protein, BH4 Bcl-2, Bcl-2 homology region 1-3 Bcl-2 family Bcl2-like Bcl-2-like superfamily
      UniProtKB:Q7T381 InterPro 211
      UniProtKB:B2GRX5 InterPro 211
      1 - 2 of 2
      Transcripts
      Genome Browsers
      Genome Build: GRCz11Chromosome: 2
      Type Name Annotation Method Has Havana Data Length (nt) Analysis
      mRNA bokb-201 (1) Ensembl 1,509 nt
      1 - 1 of 1
      Interactions and Pathways
      No data available
      Antibodies
      No data available
      Plasmids
      No data available
      Constructs
      No data available
      Marker Relationships
      Relationship Marker Type Marker Accession Numbers Citations
      Contained inBACCH211-105D4ZFIN Curated Data
      EncodescDNAMGC:64041ZFIN Curated Data
      EncodescDNAMGC:192385ZFIN Curated Data
      1 - 3 of 3
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      Sequences
      Orthology
      Comparative Orthology
      Alliance
      Gene Tree
      Ensembl
      Species Symbol Chromosome Accession # Evidence
      HumanBOK2
      Conserved genome location (synteny) (1)
      Amino acid sequence comparison (1)
      MouseBok1
      Amino acid sequence comparison (1)
      Conserved genome location (synteny) (1)
      Citations
      1 - 9 of 9
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