Gene

arrb2b

ID

ZDB-GENE-040426-1332

Name

arrestin, beta 2b

Symbol

arrb2b Nomenclature History

Previous Names

arrb2
ARRB2b2 (1)
zgc:64007

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have angiotensin receptor binding activity. Involved in muscle organ development; regulation of receptor recycling; and regulation of signal transduction. Predicted to localize to cytoplasm. Is expressed in several structures, including alar plate midbrain region; axis; brain; vasculature; and ventral mesoderm. Orthologous to human ARRB2 (arrestin beta 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64007 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arrb2b Human Ortholog

No data available

Associated With arrb2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017864	Arrestin, conserved site
Domain	IPR011021	Arrestin-like, N-terminal
Domain	IPR011022	Arrestin C-terminal-like domain
Family	IPR000698	Arrestin
Homologous_superfamily	IPR014752	Arrestin-like, C-terminal
Homologous_superfamily	IPR014753	Arrestin, N-terminal
Homologous_superfamily	IPR014756	Immunoglobulin E-set

Domain Details Per Protein

Protein	Length	Arrestin	Arrestin, conserved site	Arrestin C-terminal-like domain	Arrestin-like, C-terminal	Arrestin-like, N-terminal	Arrestin, N-terminal	Immunoglobulin E-set
UniProtKB:A0A8M3AU12 InterPro	334
UniProtKB:A0A8M3B109 InterPro	420
UniProtKB:A0A8M3B3X5 InterPro	420
UniProtKB:Q7T2D2 InterPro	408

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arrb2b-201 (1) Ensembl	Ensembl	4,613 nt	Select Tool ZFIN BLAST
ncRNA	arrb2b-002 (1) Ensembl	Ensembl	719 nt	Select Tool ZFIN BLAST
ncRNA	arrb2b-003 (1) Ensembl	Ensembl	636 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations